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Polycystic Ovary Syndrome- A silent epidemic

  • Cause of the disease is largely unknown, with research now pointing to lifestyle, genetics and even chronic stress. 
  • PCOD is the fourth phenotype of PCOS, if Rotterdam criteria is considered.
  • Unfortunately, other than mitigating symptoms with medications and lifestyle changes, PCOS research-wise is yet a black hole, to be understood.

 

According to a recent research published by WHO in 2023, PCOS affects upto 8-13% women of reproductive age globally. To add on to it, 70% of these cases go undiagnosed, because most of the women do not know what and when to reach out to a physician. 

 

Why does this happen? How can such a large number of cases go undiagnosed and severely untreated? 

This is owing to the fact that PCOS symptoms vary largely amongst individuals.

However, irregular periods, and infertility are few of the most common of them all. 

 

Why does PCOS occur? And, how come we are suddenly in the middle of an epidemic?

The exact cause, to the nightmare of women, is largely unknown. However, research does point to multiple factorial play. Imagine a toddler with a lego set? And, now visualize him breaking it all, in one go. That’s how PCOS is. 

 

Scientifically, four major factors influence PCOS: 

  1. Environmental toxin
  2. Genetic predisposition
  3. Gut dysbiosis
  4. Diet/lifestyle- recent studies also have pointed to chronic stress to be one of the reasons. 

 

These inturn influence hormone balance leading to hyperandrogenism and insulin resistance, which most prominently show-up in women with PCOS as unwanted hair and eventually diabetes. Apart from physiological symptoms, PCOS can also cause negative body image, anxiety and depression. Certain physiological symptoms, like infertility, can also lead to social stigma affecting the mental health of the individual.

Answering Your Questions

Why does this happen? How can such a large number of cases go undiagnosed and severely untreated?

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Though they may sound really similar, just a matter of a single letter in the acronym, but PCOS is different from PCOD. In PCOS, endocrine imbalance leads to excessive androgen production by the ovaries. In such cases, eggs are prone to becoming cysts. On the other hand, PCOD is a condition where ovaries release immature eggs and result in swollen ovaries along with hormonal imbalance. PCOS being an endocrine disorder, almost always requires external hormone intake. Moreover, PCOD is far more common amongst women as compared to PCOS.

Is there any treatment available for PCOS?

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Unfortunately, no panacea is known yet for PCOS. However, it can be managed and the symptoms kept in check. Lifestyle choices, diet and exercise can help reduce the risk of type 2 diabetes. Menstrual cycles can also be regulated with the help of birth control pills, if need be. We recommend you consult your gynaecologist for your specific situation.

What can I do if I know someone with PCOS?

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LEARN: It is imperative that we stop sweeping topics like menstruation under the carpet. Research, dissemination of accurate information and uprooting the stigma associated with reproductive health can go a long way in improving the lives of millions. So, learning about PCOS is the step one. LISTEN: Listen to their specific needs. PCOS looks different on everyone, and most of them do not need a reminder to lose weight/wax but a compassionate ear. For people with PCOS, the menstrual cycle can be very uniquely different from the typical cycle. PMS, bloating, and even continuous lethargy could be part of their cycle. LEND: Lend your hand and share the word, for awareness.

Sources: Pubmed Central, NHI, JHU, WHO

Authors: Aishwarya Ganapathy & Prerna Srirajsi, volunteers at Pratisandhi

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